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The Pathogen Detection Services Laboratory (PDSL), located at the Washington National Biomedical Research Center (WaNBRC) in Seattle, is a resource for analytical assays and specialized nonhuman primate materials used for analytical testing. The PDSL regularly monitors all WaNBRC nonhuman primates (NHP) and externally submitted specimens to help maintain and enhance the overall health of macaques. The monitoring also serves as the basis for segregating NHP into stratified Specific Pathogen Free (SPF) colony levels. All of the following assays, reagents, and services are for research use only (RUO). PDSL is not a licensed diagnostic laboratory, but we specialize in detection of nonhuman primate infectious agents. PDSL does not accept human samples.
Most recent update 4/9/2026
Serology (Luminex panel and immunoblots/IFAs) and PCR (non-quantitative, cutpoint assays), RUO
- Type D simian retrovirus (SRV) – serotypes 1-5 serology and PCR
- Simian T cell leukemia virus (STLV1 and STLV2) serology and PCR (on request)
- Macaque herpesvirus 1 (B virus) – serology
- Simian immunodeficiency virus (SIV or SHIV)– serology and PCR (on-request)
- Simian varicella virus (SVV) – serology and PCR
- Measles virus – serology
- T. cruzi (Chagas disease) – serology and PCR
- Coccidioides – serology and PCR
- Campylobacter multiplex PCR – distinguished C. jejuni from C. coli
- Upper Respiratory Tract multiplex PCR – Pseudomonas aeruginosa, Proteus mirabilis, Chlamydia pneumoniae, Moraxella catarrhalis
- Adenovirus multiplex PCR panel 2, – Adenovirus A, Adenovirus D, Adenovirus F type 40, Adenovirus F type 41
- Adenovirus multiplex PCR panel 1 – Adenovirus B1, Adenovirus B2, Adenovirus C, Adenovirus E
- Pan rhinovirus/enterovirus multiplex PCR – Human Rhinovirus types A, B, and C, Enteroviruses A71 and D68 and other A and D types, Coxsackievirus types A and B, Poliovirus types 1, 2, and 3
- PAN-coronavirus serology panel detects antibodies to N and S proteins of SARS-CoV-2 and seasonal strains 229E, NL-63, OC43 and HKU-1
Multiplex PCR to detect SARS-CoV-2, Influenza A, Influenza B in one swab sample. - In development (estimated timeline for validation)
- Fetal gender determination using pregnant female plasma (August 2026)
- Air filter PCR testing – (July 2026)
BioFire system Multiplex Pathogen Panels – Multiplex PCR detection( non-quantitative) – RUO, not for diagnostic results
One swab sample is required to test an animal for each panel of pathogens:
- Respiratory pathogen panel (includes SARS-CoV-2 and 20 others pathogens)
- Gastrointestinal panel (Includes bacteria, viruses, parasites, 22 total pathogens)
Specialized NHP pathogen reagents and assays. RUO
- SRV 1, 2, 3, 4, 5 purified antigen preparations (~1 mg/ml)
- SRV1-5 and SVV cell culture preparations
- SRV, SVV DNA preparations from cell culture (PCR controls)
- SRV plasma (POS and NEG controls plasma for immunoassays)
- SVV plasma (POS and NEG control)
- SRV recombinant proteins for immunoassays (gp70 and gp90)
- SERV (beta-SERV) recombinant proteins for immunoassays (gp70 and gp90)
- SRV immunoblots (SRV1, 2, 3, 4, 5)
- Herpes B recombinant proteins Gly D and Gly B
- T cruzi infected tissue confirmed by PCR
- T cruzi positive plasma
- IFAs for detection of antibodies to T cruzi, Herpes B, Simian Varicella, Measles
Additional Resources